Q. Which pets are receiving transplants with Embryll’s cloned embryonic primary cells?
A. The cells are currently transplanted to dogs and cats. Shortly, the target for transplantation will be expanded to other pets.
Q. Are there any restrictions on the age or health status of pets to receive cell transplantation?
A. There are no special restrictions. However, it is advisable to prepare for transplantation ahead before a pet is about to die due to a serious illness or becomes too old, as it takes about three months on average to manufacture the cells.
Q. I would like to transplant young bone marrow into my aging pet. How do I get started?
A. Bone marrow transplantation is as simple as a blood transfusion, so it can be operated sufficiently even in a small animal clinic. Visit your nearest veterinarian and tell the veterinarian that you would like to transplant young bone marrow prepared from Embryll into your aging pet. The next step will be led by your veterinarian and Embryll.
Q. Can pets receive cell transplantation outside of the United States?
A. Yes, of course.
Q. Is FDA approval needed before cell transplantation?
A. Similar to Cocker Spaniel Millie, who was diagnosed with a life expectancy of less than 6 months, pets with blood cancer often receive bone marrow transplantation. FDA approval is not needed in this case. Likewise, FDA approval is not required if Embryll’s cloned embryonic primary cells are transplanted through veterinarians.
Q. How much does cell transplantation cost?
A. The owner of a pet will pay all expenses directly to a veterinarian. Therefore, you have to ask a veterinarian about the cost.
Q. How are the tissues collected?
A. A veterinarian collects small tissues about 5 mm in diameter from a pet’s skin. Veterinarians are usually familiar with tissue collection. Collecting tissues is typically completed in 5 minutes, and no special post-op care is needed for a pet after the collection. Therefore, you can take the pet home right after the collection is completed. The collected tissues are put in a special preservation solution sent from Embryll in advance, and they are shipped to Embryll’s laboratory immediately.
Q. Is general anesthesia used during cell transplantation?
A. This is a matter for the veterinarian to decide. The veterinarian will comprehensively review the types of cells to be transplanted and the pet’s health condition. If necessary, the veterinarian will be able to administer sedatives, local anesthesia, or general anesthesia.
Q. Can Embryll’s cloned embryonic primary cells be transplanted into humans as well?
A. Currently, it is impossible to transplant cloned embryonic primary cells into humans. That is because some steps (e.g., transferring and retrieving cloned embryos from a surrogate mother’s uterus) in the process of manufacturing cells are not legally allowed. Embryll is seeking new solutions that can substitute these steps in artificial uteruses, organoids, and bioprinting.